For 2015-16, the Orange County Department of Education and the OC STEM Initiative announced the following Lead STEM Practitioners:
- Kelley Barrett, Anaheim City School District
- Jack Gupton, Anaheim Union High School District
- Clay Elliott, Anaheim Union High School District
- Mary Koga, Brea Olinda Unified
- Emily Bruhns, Buena Park School District
- Amy Varricchio, Capistrano Unified School District
- Kellie Little, Capistrano Unified School District
- Jennifer Faulhaber, Centralia Elementary School District
- Melinda Steele, Cypress School District
- Viet Nguyen, Fountain Valley School District
- Holly Steele, Fullerton School District
- Monica Nash, Huntington Beach City School District
- Joseph Archival, Huntington Beach Union High School District
- Greg Gardiner, Huntington Beach Union High School District
- Kristen Winn, Irvine Unified School District
- Olga Cammer, La Harbra City School District
- Dustin Gowen, Laguna Beach School District
- Carrie Denton, Laguna Beach School District
- Trisha Callella, Los Alamitos Unified School District
- Eric Chittum, Lowell Joint School District
- Jennifer Cornejo, Magnolia School District
- Diana Thompson, Newport-Mesa Unified School District
- Sandi Lewis, Ocean View School District
- Marcia Garten, Orange County Department of Education
- Cara Pettite, Orange County Department of Education
- Julie Roney, Orange Unified School District
- Laura Kresl, Orange Unified School District
- Jenner Rasic, Placentia Yorba Linda Unified School District
- Katie Degraffenreid, Placentia Yorba Linda Unified School District
- Laurie Nelson, Saddleback Valley Unified School District
- Jan Ernsbarger, Saddleback Valley Unified School District
- Lizette Cabrera, Santa Ana Unified School District
- Ruth Abatzoglou, Santa Ana Unified School District
- Kristin Hartloff, Tustin Unified School District
- Denis Cruz, Westminster School District